This laboratory was inaugurated by Dr. Silke Krol, Italy in 2012. Basic research on cancer cells was started with
the aim to translate the therapeutic non-invasive modalities from bench to bedside. PRL has initiated Photodynamic therapy
(PDT) on different cancer cells for the first time in the country in collaboration with National Institute of Health (NIH),
Pakistan and Harvard Medical School, USA for better therapeutic outcome. Different therapeutic modalities such as PDT, chemo,
medicinal etc., alone and in combination were administered on different human cancer cell lines i.e., HeLa, RD, Hep2c, and Hep2.
Researcher from other universities are utilizing this laboratory frequently and are always warmly welcomed to work in PRL Lab
on research problems related to the field of Photodynamic therapy.
Photonanomedicine Research Laboratory has gained a lot of attention of researchers in a very short time due to its significant
contributions on various projects related to cancer therapy. PRL also won funding under NRPU for development of polymeric nano-carrier.
Currently, the main focused is on polymeric nano-drug delivery due to its biocompatibility and biodistribution.
We are also plan to divert our expertise in computational model for biomedical application.
Team Members
Group members who always work hard to provide quality teaching & Research.
MSc Genetics (University of Karachi, Karachi)
MSc Cell & Enzyme Technology (University of Central Lancashire, UK)
Research Interests: Biophotonics, Photo-Medicine
E-mail: junaid@pieas.edu.pk
Dr. Muhammad Tariq Siddique
Assistant Professor, DPAM
PhD Nuclear Engineering (Kyung-Hee University, South Korea)
MSc Medical Physics (PIEAS, Islamabad)
MSc Physics (UET, Lahore)
Research Interest: Research Interests: Radiation Physics and Dosimetry,
Nuclear Reactor Physics and Analysis, Computational Methods for Nuclear
Reactor Core Analysis, Fusion Fission Hybrid Reactor Design and Analysis
E-mail: tariqs@pieas.edu.pk
Dr. Syed Mujtaba-ul-Hassan
Assistant Professor, DMME
PhD Innovative & Engineered Materials (Tokyo Institute of Technology, Japan)
MS Nuclear Engineering (PIEAS, Islamabad)
BSc Hons Metallurgical Engineering & Material Science (UET, Lahore)
Research Interests: Research interestes: Nanoparticles based contrast
agents, Nano theranostics, Inorganic nanoparticles for drug delivery,
magneto flourscencent nanoparticles for biomedical applications
E-mail: mujtaba@pieas.edu.pk
MS. Bushra Aziz
PhD scholar, DPAM
M.Phil Physics (University of Azad Jammu & Kashmir, Muzaffarabad, Pakistan)
MSc Physics ( University of Azad Jammu & Kashmir, Muzaffarabad, Pakistan)
Research Interests: Nanotechnology, metal oxide Nanomaterials, Nanodrug delivery carriers, Photo-dynamic Therapy, Phyto-Therapy
E-mail: bushra_aziz_18@pieas.edu.pk; bushra_aziz87@yahho.com
Ms. Saba Naz
PhD scholar, DPAM
MS Physics (International Islamic University, Islamabad, Pakistan)
MSc Physics (International Islamic University Islamabad, Pakistan)
Research Interests: Nanotechnology, Magnetic Nanomaterials, Nanodrug delivery system, Photodynamic Therapy
E-mail: sabanaz_19@pieas.edu.pk; Sabach047@gmail.com
BS Chemistry
Research Interest: polymer Nano particles
E-mail: saleemktk25@gmail.com
Ms. Uswah Zainab
MS Student, DPAM
Bs Chemistry
Research Interest: My professional goals align with the advances in research that point to adantage the environment,
moderate and deliver strength make strides human life, and extend our information of the universe.
I want to do research on antioxidants, nanoparticles.
E-mail: zainabuswah6@gmail.com
Ms. Sumbal Javaid
PhD scholar (Visiting)
M. Phil in Biological Sciences
Research Interest: Cancer therapeutics
E-mail: sumbalshakeel86@gmail.com
Mr. Izaz ahmad
MS Student, DPAM
BS physics
Research Interest: Bio Medical physics
E-mail: izazahmad7236@gmail.com
Ms. Maryam Yaqub
BS Student, DPAM
BS
Research Interest: in-vitro drug delivery vehicle, Nano Particle synthesis
E-mail: maryamyaqub99@gmail.com
Ms. Pakeeza
BS Student, DPAM
Research Interest: in-vitro drug delivery vehicle, Nano Particle synthesis
E-mail:
Publications
Numrah Sultan,Syed Mujtaba ul Hassan, Ahmat Khurshid,Zahid Ali, Attaullah Shah, Jamil Ahmad, PhDPEGylated Eu-enabled submicron alumina spheres as potential theranostic agent, Materials Chemistry and Physics (submitted January 2021).
R.Mahmood, A. Khurshid, M.S.Yousaf, M.Aalam, M.Salman, M.Ikram, Effect of Vitamin A as a Neoadjuvant Agent in Chemotherapy and Photodynamic Therapy of Rhabdomyosarcoma Cells, Photodiagnosis and Photodynamic Therapy, November 2020. [IF = 2.894].
Yousaf MS, Khurshid A, Mahmood R, Ikram M, Polarimetric comparison of fresh and frozen skeletal muscle tissues of goat, Photodiagnosis and Photodynamic Therapy October 2020. [IF = 2.894].
Muhammad Zakir, Ahmat Khurshid, Muhammad Iqbal Khan, Asma Khattak, Murad Ali Khan, The application of Aluminium Phthalocyanine (AlPs-4) mediated Photodynamic Therapy against human soft tissue sarcoma(RMS) cell line, Journal of Porphyrins and Phthalocyanines, October 2020. [IF = 1.816]
Syed Mujtaba ul Hassan, Tanzeela Anis, Ahmat Khurshid, Faisal Shahzad, Zafar Iqbal, Muhammad Zahid, Attaullah Shah, Jamil Ahmad, Mazhar Mehmood, Facile synthesis of multifunctional m-SiO2@ZnO nanocomposite employing biocompatible polymers for potential theranostic applications Micro & Nano Letters, September 2020. [IF = 0.43]
Numrah Sultan, Syed Mujtaba ul Hassan, Jamil Ahmed, Ahmat Khurshid, Zahid Ali, and Attaulllah Shah, Facile Hydrothermal fabrication of Eu doped alumina for Potential Bioluminescent Imaging and Drug Delivery System, Key Engineering Materials journal, April 2020. [IF = 0.9]
Tayyab Ali Khan, Syed Mujtaba ul Hassan, Hassan Waqas, Jamil Ahmad, Ahmat Khurshid, Mazhar Mehmood, Hafiz Muhammad Bin Ahmed, and Sumaira Naz, Evaluation of Potential of Uncoated Mesoporous Silica Particles for Drug Delivery Applications, Key Engineering Materials journal, April 2020. [IF = 0.9].
S. Yousaf, A. Khurshid, I. Ahmad, R. Mahmood, M. Alam, S. B. Bukhari, J. Ahmad Khan, M. Rafi, M. Ikram, Label free characterization of soft tissue with optical polarization technique, Laser Physics, 30(2020). [IF = 2.894].
S. Yousaf, I. Ahmad, A. Khurshid, M. Ikram Machine assisted classification of chicken, beef and mutton tissues using optical polarimetry and Bagging model, Photodiagnosis and Photodynamic Therapy 31 (2020). [IF = 2.894].
Ali Khan, S. Mujtaba ul Hassan, J. Ahmad, A. Khurshid, M. Mehmood, H. Waqas, F. Ali, Fabrication of PEGylated Porous Alumina whiskers (PAW) for drug delivery Applications, Material Letters, 241, 23-46(2019). [IF = 2.687]
R. Mahmood , A. khurshid , , J. A. Khan, M.Rafi, M. S. Yousaf, M. Maqsood, M. Alam, M. Salman and M. Ikram Enhanced efficacy of chemo-photodynamic therapy of rhabdomayosarcoma cells by using vitamin K3 as a neoadjuvant agent, Laser Phys. 29 2019. [IF = 1.102]
R. Mahmood , A. khurshid , M. Maqsood, J. A. Khan, M.Rafi, S. S. Z. Zaidi, M. Ikram “Vitamin D3-assisted Chemo-Photodynamic therapy of Rhabdomyo sarcoma cancer cells for effective treatment” Laser Phys. Lett. 15 2018. [IF = 2.39]
S. Ali, S. Muhammad, A. Khurshid, M. Ikram, M. Maqsood, C. Fisher, J. Cathcart, L. Lilge, Effective phthalocyanines mediated photodynamic therapy with doxorubicin or methotrexate combination therapy at sub-micromolar concentrations in vitro, Photodiagnosis and Photodynamic Therapy, volume 22, pp 51-64, June 2018. [IF = 2.89]
S. Ali, S. Muhammad, A. Khurshid, M. Ikram, M. Maqsood, C. Fisher, J. Cathcart, L. Lilge, Doxorubicin or Methotrexate exposure followed by Aluminum Phthalocyanine mediated Photodynamic Therapy provides for effective co-therapy, Photochemistry and Photobiology, volume 17, pp A46, 2017.[IF = 2.89]
I. Ahmad, A. Rehman, J. A. Khan, M. Rafi, A. Khurshid, H. Nisar, S. S. Z. Zaidi, M. Ikram, Effects of varying local temperature on the optical properties of cells In-Vitro, Photodiagnostic and Photodynamic Therapy, 12(3): 459-65 (2015). [IF = 2.89]
S. Ali, A. Khurshid, M. Maqsood, M. Rafi, J. A. Khan, S. S. Z. Zaidi , S. Muhammad, M. Ikram , Study of low doses Cisplatin synergestic effect on photodynamic outcome of Al (II)-phythalocyanine on soft tissue sarcoma (RD) cell line, Photodiagnostic and Photodynamic Therapy, 12(1):146-9, 2015.[IF = 2.89]
M. Ahmad, S. Ali, M. S. Mehmood, H. Ali, A. Khurshid , S. Firdous, S. Muhammad, M. Ikram, Ex vivo assessment of carbon tetrachloride (CCl4) induced chronic injury using polarized light spectroscopy. Journal of Applied Spectroscopy, 67 (12), 2013. [IF= 1.942]
Khizar Hayat, A. Khurshid, M. A. Rafiq, S. K. Durrani, S. S. Z. Zaidi, M. Ikram and M. M. Hasan, PEGylated BaMnO3 Nanoparticles Potential as a Drug delivery Agent, Laser physics letter, 10, 2013. [IF= 2.458]
A. Khurshid, S. Firdous, L. Ahmat, J. Ferraira, J. D. Vollet-Filho, C. Kurachi, V. S. Bagneto, M. Nawaz, M. Ikram and M. Ahmad, In Vivo study of laser irradiation of fractionated drug administration based mechanism for effective photodynamic therapy in rat liver, Laser Physics, 22(1) 317-321(2012). [IF= 1.032]
R. Prakash, M. Surivallesha, Z. Xiang, R. Ramtin, M. Youssef, E. Stefan, A. Khurshid, T. Hasan, Development and Application of Photo-Triggered Theranostic Agents. Advanced Drug Delivery Reviews 62, 1094-1124(2010). [IF= 12.888]
A. Khurshid, M. Atif , S. Firdous, S. S. Z. Zaidi, R. Salman and M. Ikram, Study of the efficacy of 5 ALA-mediated photodynamic therapy on human larynx squamous cell carcinoma (Hep2c) cell line, Laser Phys. 20(7),1673-1678(2010). [IF= 1.032]
M. Atif, S. Firdous, A. Khurshid, L. Noreen, S .S .Z. Zaidi and M. Ikram, In vitro study of 5-aminolevulinic acid-based photodynamic therapy for apoptosis in human cervical HeLa cell line, Laser Phys. Lett. 6(12), 886–891 (2009). [IF= 2.458]
Programs
PhD Nuclear Engineering
Since1988
PhD in nuclear engineering includes course work, qualifying exams and an original research work on a topic of choice in nuclear engineering. PhD thesis requires an international review and publications in reputed journals. At present various PhD scholars are conducting their doctoral level research in various fields of nuclear engineering in the department.
PhD Radiation Physics
Since2014
PhD in radiation physics includes course work, qualifying exams and an original research work on a topic of choice in radiation physics. PhD thesis requires an international review and publications in reputed journals. At present various PhD scholars are conducting their doctoral level research in various fields of radiation physics in the department.
This program is by far the oldest at PIEAS. More than 1300 engineers and scientists have graduated under this program over the past four decades and today they form the backbone of various projects of the Pakistan Atomic Energy Commission and other strategic organizations. The participants of this program are taken from almost all the engineering and scientific disciplines. This diversity is just one of the imperatives of the multi-disciplinary nature of nuclear engineering itself. It has always been a stimulating challenge for the faculty to guide a group of people with different backgrounds towards the unified goal of understanding the complex systems and processes involved in nuclear technology.
The MS Radiation Physics program was launched in 2014 to meet the requirements of PAEC for expansion of Nuclear Power Program along with allied Nuclear Fuel Cycle Facilities. The program aims at development of graduate students in the area of Radiological Protection, Environmental Dispersion, NPPs impact Monitoring & Dosimetry, Radioactive Waste Management, Nuclear Emergency Handling, NPPs Site Selection, Reliability & Risk Assessment and Nuclear Safety Analysis.
Department is equipped with advanced laboratories including Health Physics Lab., Radiation Shielding Lab., Radiation Interaction and Detection Lab., Environmental Monitoring Lab., Advanced Computational Reactor Engineering Lab., PWR Simulation Lab., and Hazardous Air Pollutants Lab. The degree is offered to the students having 2-year M.Sc. Physics degree or a 4-year B.S. Physics degree.
Events
Latest Events arranged in Center for Mathematical Sciences.
Single Crystal Growth and its Application in Radiation Detection
